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Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells

rDNA loci, composed of hundreds of tandemly duplicated arrays of rRNA genes, are known to be among the most unstable genetic elements due to their repetitive nature. rDNA instability underlies aging (replicative senescence) in yeast cells, however, its contribution to the aging of multicellular orga...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Lu, Kevin L, Nelson, Jonathan O, Watase, George J, Warsinger-Pepe, Natalie, Yamashita, Yukiko M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811208/
https://ncbi.nlm.nih.gov/pubmed/29436367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32421
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