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Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells

rDNA loci, composed of hundreds of tandemly duplicated arrays of rRNA genes, are known to be among the most unstable genetic elements due to their repetitive nature. rDNA instability underlies aging (replicative senescence) in yeast cells, however, its contribution to the aging of multicellular orga...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Lu, Kevin L, Nelson, Jonathan O, Watase, George J, Warsinger-Pepe, Natalie, Yamashita, Yukiko M
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811208/
https://ncbi.nlm.nih.gov/pubmed/29436367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32421
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