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Mechanisms of rDNA copy number maintenance

Ribosomal DNA (rDNA), the genes encoding the RNA components of ribosomes (rRNA), are highly repetitive in all eukaryotic genomes, containing 100s to 1000s of copies, to meet the demand for ribosome biogenesis. rDNA genes are arranged in large stretches of tandem repeats, forming loci that are highly...

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Publicado en:Trends Genet
Autores principales: Nelson, Jonathan O., Watase, George J., Warsinger-Pepe, Natalie, Yamashita, Yukiko M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744303/
https://ncbi.nlm.nih.gov/pubmed/31395390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2019.07.006
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