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A Human STAT1 Gain-of-Function Mutation Impairs CD8(+) T Cell Responses against Gammaherpesvirus 68
Autosomal dominant STAT1 mutations in humans have been associated with chronic mucocutaneous candidiasis (CMC), as well as with increased susceptibility to herpesvirus infections. Prior studies have focused on mucosal and Th17-mediated immunity against Candida, but mechanisms of impaired antiviral i...
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| 發表在: | J Virol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744239/ https://ncbi.nlm.nih.gov/pubmed/31315996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00307-19 |
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