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A Human STAT1 Gain-of-Function Mutation Impairs CD8(+) T Cell Responses against Gammaherpesvirus 68
Autosomal dominant STAT1 mutations in humans have been associated with chronic mucocutaneous candidiasis (CMC), as well as with increased susceptibility to herpesvirus infections. Prior studies have focused on mucosal and Th17-mediated immunity against Candida, but mechanisms of impaired antiviral i...
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| Publié dans: | J Virol |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744239/ https://ncbi.nlm.nih.gov/pubmed/31315996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00307-19 |
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