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Primary Clearance of Murine Gammaherpesvirus 68 by PKCθ(−/−) CD8 T Cells Is Compromised in the Absence of Help from CD4 T Cells
CD4 T cells are dispensable for acute control of murine gammaherpesvirus 68 (MHV-68) but are necessary for effective long-term control of the virus by CD8 T cells. In contrast, protein kinase C θ (PKCθ) is not essential for either acute or long-term viral control. However, we found that while either...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583662/ https://ncbi.nlm.nih.gov/pubmed/18818318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01053-08 |
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