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CD40 Engagement on Dendritic Cells, but Not on B or T Cells, Is Required for Long-Term Control of Murine Gammaherpesvirus 68

CD4 T cells are not essential for primary clearance of replicating murine gammaherpesvirus 68 (MHV-68) but are required for effective long-term control. The virus reactivates in the lungs of major histocompatibility complex class II-deficient (CII−/−) mice that lack functional CD4 T cells. CD40 liga...

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Detalhes bibliográficos
Main Authors: Giannoni, Francesca, Shea, Ashley, Inglis, Chandra, Lee, Lian Ni, Sarawar, Sally R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573265/
https://ncbi.nlm.nih.gov/pubmed/18768977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00919-08
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