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Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation

The nucleus houses, organizes, and protects chromatin to ensure genome integrity and proper gene expression, but how the nucleus adapts mechanically to changes in the extracellular environment is poorly understood. Recent studies have revealed that extracellular physical stresses induce chromatin co...

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Podrobná bibliografie
Vydáno v:Mol Biol Cell
Hlavní autoři: Stephens, Andrew D., Liu, Patrick Z., Kandula, Viswajit, Chen, Haimei, Almassalha, Luay M., Herman, Cameron, Backman, Vadim, O’Halloran, Thomas, Adam, Stephen A., Goldman, Robert D., Banigan, Edward J., Marko, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743459/
https://ncbi.nlm.nih.gov/pubmed/31365328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-05-0286
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