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Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells
Emery-Dreifuss muscular dystrophy can be caused by mutations in the nuclear envelope proteins lamin A/C and emerin. We recently demonstrated that A-type lamin-deficient cells have impaired nuclear mechanics and altered mechanotransduction, suggesting two potential disease mechanisms (Lammerding, J.,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171355/ https://ncbi.nlm.nih.gov/pubmed/16115958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200502148 |
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