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The Driving Force: Nuclear Mechanotransduction in Cellular Function, Fate, and Disease

Cellular behavior is continuously affected by microenvironmental forces through the process of mechanotransduction, in which mechanical stimuli are rapidly converted to biochemical responses. Mounting evidence suggests that the nucleus itself is a mechanoresponsive element, reacting to cytoskeletal...

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Detalhes bibliográficos
Publicado no:Annu Rev Biomed Eng
Main Authors: Maurer, Melanie, Lammerding, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815102/
https://ncbi.nlm.nih.gov/pubmed/30916994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-bioeng-060418-052139
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