Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation

The nucleus houses, organizes, and protects chromatin to ensure genome integrity and proper gene expression, but how the nucleus adapts mechanically to changes in the extracellular environment is poorly understood. Recent studies have revealed that extracellular physical stresses induce chromatin co...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Stephens, Andrew D., Liu, Patrick Z., Kandula, Viswajit, Chen, Haimei, Almassalha, Luay M., Herman, Cameron, Backman, Vadim, O’Halloran, Thomas, Adam, Stephen A., Goldman, Robert D., Banigan, Edward J., Marko, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743459/
https://ncbi.nlm.nih.gov/pubmed/31365328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-05-0286
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