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Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins
Nuclear shape and architecture influence gene localization, mechanotransduction, transcription, and cell function. Abnormal nuclear morphology and protrusions termed “blebs” are diagnostic markers for many human afflictions including heart disease, aging, progeria, and cancer. Nuclear blebs are asso...
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| Publicado en: | Mol Biol Cell |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5909933/ https://ncbi.nlm.nih.gov/pubmed/29142071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-06-0410 |
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