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Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

The cell nucleus must continually resist and respond to intercellular and intracellular mechanical forces to transduce mechanical signals and maintain proper genome organization and expression. Altered nuclear mechanics is associated with many human diseases, including heart disease, progeria, and c...

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Publicado en:Mol Biol Cell
Autores principales: Stephens, Andrew D., Banigan, Edward J., Adam, Stephen A., Goldman, Robert D., Marko, John F.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541848/
https://ncbi.nlm.nih.gov/pubmed/28057760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-09-0653
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