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Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

The cell nucleus must continually resist and respond to intercellular and intracellular mechanical forces to transduce mechanical signals and maintain proper genome organization and expression. Altered nuclear mechanics is associated with many human diseases, including heart disease, progeria, and c...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Stephens, Andrew D., Banigan, Edward J., Adam, Stephen A., Goldman, Robert D., Marko, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541848/
https://ncbi.nlm.nih.gov/pubmed/28057760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-09-0653
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