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Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

The cell nucleus must continually resist and respond to intercellular and intracellular mechanical forces to transduce mechanical signals and maintain proper genome organization and expression. Altered nuclear mechanics is associated with many human diseases, including heart disease, progeria, and c...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Stephens, Andrew D., Banigan, Edward J., Adam, Stephen A., Goldman, Robert D., Marko, John F.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541848/
https://ncbi.nlm.nih.gov/pubmed/28057760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-09-0653
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