Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice

The degenerative process of Alzheimer's disease is linked to a shift in the balance between amyloid-β (Aβ) production, clearance, and degradation. Neprilysin has recently been implicated as a major extracellular Aβ degrading enzyme in the brain. However, there has been no direct demonstration t...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Marr, Robert A., Rockenstein, Edward, Mukherjee, Atish, Kindy, Mark S., Hersh, Louis B., Gage, Fred H., Verma, Inder M., Masliah, Eliezer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2003
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Brief Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742010/
https://ncbi.nlm.nih.gov/pubmed/12657655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-06-01992.2003
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