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De novo MET amplification promotes intrinsic resistance to first-generation EGFR tyrosine kinase inhibitors
First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) could induce dramatic tumor responses in non-small-cell lung cancer patients with EGFR-activating mutations. However, a small proportion of patients have no tumor response on initial EGFR TKI treatment with an...
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| Publicado no: | Cancer Biol Ther |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6741769/ https://ncbi.nlm.nih.gov/pubmed/31131689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2019.1617568 |
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