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Next-Generation EGFR Tyrosine Kinase Inhibitors for Treating EGFR-Mutant Lung Cancer beyond First Line

Tyrosine kinase inhibitors (TKIs) against the human epidermal growth factor receptor (EGFR) are now standard treatment in the clinic for patients with advanced EGFR mutant non-small-cell lung cancer (NSCLC). First-generation EGFR TKIs, binding competitively and reversibly to the ATP-binding site of...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Sullivan, Ivana, Planchard, David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241298/
https://ncbi.nlm.nih.gov/pubmed/28149837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2016.00076
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