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Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors

Patients with non-small-cell lung cancer (NSCLC) whose tumours harbour activating mutations within the epidermal growth factor receptor (EGFR) frequently derive significant clinical and radiographic benefits from treatment with EGFR tyrosine kinase inhibitors (TKIs). As such, prospective identificat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ann Oncol
Päätekijät: Westover, D, Zugazagoitia, J, Cho, B C, Lovly, C M, Paz-Ares, L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454547/
https://ncbi.nlm.nih.gov/pubmed/29462254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx703
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