ABT‐089: Pharmacological Properties of a Neuronal Nicotinic Acetylcholine Receptor Agonist for the Potential Treatment of Cognitive Disorders

ABT‐089 [2‐methyl‐3‐(2‐(S)‐pyrrolidinylmethoxy)pyridine dihydrochloride salt] is a selective neuronal nicotinic receptor (NNR) modulator with cognitive enhancing properties in animal models of cognitive functioning. Amongst NNR subtypes, ABT‐089 shows selectivity for the cytisine binding site on the...

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發表在:CNS Drug Rev
Main Authors: Rueter, Lynne E., Anderson, David J., Briggs, Clark A., Donnelly‐Roberts, Diana L., Gintant, Gary A., Gopalakrishnan, Murali, Lin, Nan‐Horng, Osinski, Mark A., Reinhart, Glenn A., Buckley, Michael J., Martin, Ruth L., McDermott, Jeffrey S., Preusser, Lee C., Seifert, Terese R., Su, Zhi, Cox, Bryan F., Decker, Michael W., Sullivan, James P.
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2006
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741767/
https://ncbi.nlm.nih.gov/pubmed/15179445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2004.tb00011.x
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