ABT‐089: Pharmacological Properties of a Neuronal Nicotinic Acetylcholine Receptor Agonist for the Potential Treatment of Cognitive Disorders

ABT‐089 [2‐methyl‐3‐(2‐(S)‐pyrrolidinylmethoxy)pyridine dihydrochloride salt] is a selective neuronal nicotinic receptor (NNR) modulator with cognitive enhancing properties in animal models of cognitive functioning. Amongst NNR subtypes, ABT‐089 shows selectivity for the cytisine binding site on the...

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Detalhes bibliográficos
Publicado no:CNS Drug Rev
Main Authors: Rueter, Lynne E., Anderson, David J., Briggs, Clark A., Donnelly‐Roberts, Diana L., Gintant, Gary A., Gopalakrishnan, Murali, Lin, Nan‐Horng, Osinski, Mark A., Reinhart, Glenn A., Buckley, Michael J., Martin, Ruth L., McDermott, Jeffrey S., Preusser, Lee C., Seifert, Terese R., Su, Zhi, Cox, Bryan F., Decker, Michael W., Sullivan, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741767/
https://ncbi.nlm.nih.gov/pubmed/15179445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2004.tb00011.x
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