ABT‐089: Pharmacological Properties of a Neuronal Nicotinic Acetylcholine Receptor Agonist for the Potential Treatment of Cognitive Disorders

ABT‐089 [2‐methyl‐3‐(2‐(S)‐pyrrolidinylmethoxy)pyridine dihydrochloride salt] is a selective neuronal nicotinic receptor (NNR) modulator with cognitive enhancing properties in animal models of cognitive functioning. Amongst NNR subtypes, ABT‐089 shows selectivity for the cytisine binding site on the...

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Vydáno v:CNS Drug Rev
Hlavní autoři: Rueter, Lynne E., Anderson, David J., Briggs, Clark A., Donnelly‐Roberts, Diana L., Gintant, Gary A., Gopalakrishnan, Murali, Lin, Nan‐Horng, Osinski, Mark A., Reinhart, Glenn A., Buckley, Michael J., Martin, Ruth L., McDermott, Jeffrey S., Preusser, Lee C., Seifert, Terese R., Su, Zhi, Cox, Bryan F., Decker, Michael W., Sullivan, James P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741767/
https://ncbi.nlm.nih.gov/pubmed/15179445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2004.tb00011.x
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