ABT‐089: Pharmacological Properties of a Neuronal Nicotinic Acetylcholine Receptor Agonist for the Potential Treatment of Cognitive Disorders

ABT‐089 [2‐methyl‐3‐(2‐(S)‐pyrrolidinylmethoxy)pyridine dihydrochloride salt] is a selective neuronal nicotinic receptor (NNR) modulator with cognitive enhancing properties in animal models of cognitive functioning. Amongst NNR subtypes, ABT‐089 shows selectivity for the cytisine binding site on the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:CNS Drug Rev
Prif Awduron: Rueter, Lynne E., Anderson, David J., Briggs, Clark A., Donnelly‐Roberts, Diana L., Gintant, Gary A., Gopalakrishnan, Murali, Lin, Nan‐Horng, Osinski, Mark A., Reinhart, Glenn A., Buckley, Michael J., Martin, Ruth L., McDermott, Jeffrey S., Preusser, Lee C., Seifert, Terese R., Su, Zhi, Cox, Bryan F., Decker, Michael W., Sullivan, James P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 2006
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741767/
https://ncbi.nlm.nih.gov/pubmed/15179445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2004.tb00011.x
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