ABT-089 and ABT-894 Reduce L-Dopa-Induced Dyskinesias in a Monkey Model of Parkinson’s Disease

BACKGROUND: L-dopa-induced dyskinesias (LIDs) are a serious complication of L-dopa therapy for Parkinson’s disease for which there is little treatment. Accumulating evidence shows that nicotine and nicotinic acetylcholine receptor (nAChR) drugs decrease LIDs in parkinsonian animals. Here we examined...

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Main Authors: Zhang, Danhui, Bordia, Tanuja, McGregor, Matthew, McIntosh, J. Michael, Decker, Michael W., Quik, Maryka
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990279/
https://ncbi.nlm.nih.gov/pubmed/24515328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25817
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