The α7 Nicotinic Receptor Agonist ABT-107 Decreases l-Dopa–Induced Dyskinesias in Parkinsonian Monkeys

Previous studies in Parkinsonian rats and monkeys have shown that β2-selective nicotinic acetylcholine receptor (nAChR) agonists reduce l-Dopa–induced dyskinesias (LIDs), a serious complication of l-Dopa therapy for Parkinson’s disease. Since rodent studies also suggested an involvement of α7 nAChRs...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Danhui, McGregor, Matthew, Decker, Michael W., Quik, Maryka
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2014
Konular:
Behavioral Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165030/
https://ncbi.nlm.nih.gov/pubmed/25034405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.216283
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