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The α7 Nicotinic Receptor Agonist ABT-107 Decreases l-Dopa–Induced Dyskinesias in Parkinsonian Monkeys
Previous studies in Parkinsonian rats and monkeys have shown that β2-selective nicotinic acetylcholine receptor (nAChR) agonists reduce l-Dopa–induced dyskinesias (LIDs), a serious complication of l-Dopa therapy for Parkinson’s disease. Since rodent studies also suggested an involvement of α7 nAChRs...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4165030/ https://ncbi.nlm.nih.gov/pubmed/25034405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.216283 |
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