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Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats

L-dopa therapy for Parkinson's disease leads to dyskinesias or abnormal involuntary movement (AIMs) for which there are few treatment options. Our previous data showed that nicotine administration reduced L-dopa-induced AIMs in parkinsonian monkeys and rats. To further understand how nicotine m...

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Detalhes bibliográficos
Main Authors: Huang, Luping Z., Campos, Carla, Ly, Jason, Carroll, F. Ivy, Quik, Maryka
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133531/
https://ncbi.nlm.nih.gov/pubmed/21232546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.12.032
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