Nicotinic Receptor Agonists Reduce l-DOPA–Induced Dyskinesias in a Monkey Model of Parkinson's Disease

Abnormal involuntary movements or dyskinesias are a serious complication of long-term l-DOPA treatment of Parkinson’s disease, for which there are few treatment options. Accumulating preclinical data show that nicotine decreases l-DOPA–induced dyskinesias (LIDs), suggesting that it may be a useful a...

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Hlavní autoři: Zhang, Danhui, Mallela, Archana, Sohn, David, Carroll, F. Ivy, Bencherif, Merouane, Letchworth, Sharon, Quik, Maryka
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2013
Témata:
Neuropharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781407/
https://ncbi.nlm.nih.gov/pubmed/23902940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.207639
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