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Selectivity of ABT-089 for α4β2* and α6β2* nicotinic acetylcholine receptors in brain
Numerous pharmaceutical efforts have targeted neuronal nicotinic receptors (nAChRs) for amelioration of cognitive deficits. While α4β2 and α7 are the more prominent nAChR in brain, other heteromeric nAChR can have important impact on agonist pharmacology. ABT-089 is a pioneer nAChR agonist found to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772152/ https://ncbi.nlm.nih.gov/pubmed/19481067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.05.022 |
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