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Effectiveness of Nicotinic Agonists as Desensitizers at Presynaptic α4β2- and α4α5β2-Nicotinic Acetylcholine Receptors

INTRODUCTION: Nicotine interacts with nicotinic acetylcholine receptors (nAChRs) and modifies neuronal functions. The net result of nicotine exposure is difficult to assess because multiple nAChR subtypes exist and are expressed on multiple classes of neurons. Nicotine, unlike the natural agonist ac...

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Detalhes bibliográficos
Main Authors: Wageman, Charles R., Marks, Michael J., Grady, Sharon R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920335/
https://ncbi.nlm.nih.gov/pubmed/24052501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntt146
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