Decreased Cyclin-Dependent Kinase 5 (cdk5) Activity Is Accompanied by Redistribution of cdk5 and Cytoskeletal Proteins and Increased Cytoskeletal Protein Phosphorylation in p35 Null Mice

Cdk5/p35 has been implicated in cytoskeletal protein phosphorylation in normal brain and in many human neurodegenerative disorders. Yet, mouse models of cdk5/p35 hyperactivity have not yielded corresponding changes in cytoskeletal protein phosphorylation. To elucidate the relationship between p35, c...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Hallows, Janice L., Chen, Ken, DePinho, Ronald A., Vincent, Inez
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2003
Teme:
Cellular/Molecular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740918/
https://ncbi.nlm.nih.gov/pubmed/14627648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-33-10633.2003
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