Upregulation of Sodium Channel Na(v)1.3 and Functional Involvement in Neuronal Hyperexcitability Associated with Central Neuropathic Pain after Spinal Cord Injury

Spinal cord injury (SCI) can result in hyperexcitability of dorsal horn neurons and central neuropathic pain. We hypothesized that these phenomena are consequences, in part, of dysregulated expression of voltage-gated sodium channels. Because the rapidly repriming TTX-sensitive sodium channel Na(v)1...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Hains, Bryan C., Klein, Joshua P., Saab, Carl Y., Craner, Matthew J., Black, Joel A., Waxman, Stephen G.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2003
Sujets:
Development/Plasticity/Repair
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740400/
https://ncbi.nlm.nih.gov/pubmed/14523090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-26-08881.2003
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