Upregulation of Sodium Channel Na(v)1.3 and Functional Involvement in Neuronal Hyperexcitability Associated with Central Neuropathic Pain after Spinal Cord Injury

Spinal cord injury (SCI) can result in hyperexcitability of dorsal horn neurons and central neuropathic pain. We hypothesized that these phenomena are consequences, in part, of dysregulated expression of voltage-gated sodium channels. Because the rapidly repriming TTX-sensitive sodium channel Na(v)1...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hains, Bryan C., Klein, Joshua P., Saab, Carl Y., Craner, Matthew J., Black, Joel A., Waxman, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740400/
https://ncbi.nlm.nih.gov/pubmed/14523090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-26-08881.2003
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