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Physiological and pathological roles of Apaf1 and the apoptosome

Different cellular pathways can lead to apoptosis. Apaf1 is the molecular core of the apoptosome, a multiproteic complex mediating the so‐called mitochondrial pathway of cell death. The importance of this pathway during development has been clearly demonstrated by knocking out key genes. Also, the r...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Ferraro, E., Corvaro, M., Cecconi, F.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740308/
https://ncbi.nlm.nih.gov/pubmed/12767258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2003.tb00199.x
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