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Physiological and pathological roles of Apaf1 and the apoptosome
Different cellular pathways can lead to apoptosis. Apaf1 is the molecular core of the apoptosome, a multiproteic complex mediating the so‐called mitochondrial pathway of cell death. The importance of this pathway during development has been clearly demonstrated by knocking out key genes. Also, the r...
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| Published in: | J Cell Mol Med |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Publishing Ltd
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6740308/ https://ncbi.nlm.nih.gov/pubmed/12767258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2003.tb00199.x |
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