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Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes
The Apaf-1 apoptosome is a multi-subunit caspase-activating scaffold that is assembled in response to diverse forms of cellular stress that culminate in apoptosis. To date, most studies on apoptosome composition and function have used apoptosomes reassembled from recombinant or purified proteins. Th...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC424369/ https://ncbi.nlm.nih.gov/pubmed/15103327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600210 |
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