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Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes

The Apaf-1 apoptosome is a multi-subunit caspase-activating scaffold that is assembled in response to diverse forms of cellular stress that culminate in apoptosis. To date, most studies on apoptosome composition and function have used apoptosomes reassembled from recombinant or purified proteins. Th...

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Bibliografske podrobnosti
Main Authors: Hill, Michelle M, Adrain, Colin, Duriez, Patrick J, Creagh, Emma M, Martin, Seamus J
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC424369/
https://ncbi.nlm.nih.gov/pubmed/15103327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600210
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