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Degradation of integral membrane proteins modified with the photosensitive degron module requires the cytosolic endoplasmic reticulum–associated degradation pathway

Protein quality mechanisms are fundamental for proteostasis of eukaryotic cells. Endoplasmic reticulum–associated degradation (ERAD) is a well-studied pathway that ensures quality control of secretory and endoplasmic reticulum (ER)–resident proteins. Different branches of ERAD are involved in degrad...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Scheffer, Johannes, Hasenjäger, Sophia, Taxis, Christof
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740197/
https://ncbi.nlm.nih.gov/pubmed/31411939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-12-0754
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