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Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery

Protein misfolding is monitored by a variety of cellular “quality control” systems. Endoplasmic reticulum (ER) quality control handles misfolded secretory and membrane proteins and is well characterized. However, less is known about the quality control of misfolded cytosolic proteins (CytoQC). To st...

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Bibliografiske detaljer
Main Authors: Metzger, Meredith Boyle, Maurer, Matthew J., Dancy, Beverley M., Michaelis, Susan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583311/
https://ncbi.nlm.nih.gov/pubmed/18812321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806424200
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