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Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic Reticulum Associated Degradation
Misfolded proteins in the endoplasmic reticulum (ER) are destroyed by ER-associated degradation (ERAD). Although the retrotranslocation of misfolded proteins from the ER has been reconstituted, how a polypeptide is initially selected for ERAD remains poorly defined. To address this question while co...
में बचाया:
| में प्रकाशित: | Mol Cell |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912696/ https://ncbi.nlm.nih.gov/pubmed/29677492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.03.016 |
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