Nalaganje...

Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic Reticulum Associated Degradation

Misfolded proteins in the endoplasmic reticulum (ER) are destroyed by ER-associated degradation (ERAD). Although the retrotranslocation of misfolded proteins from the ER has been reconstituted, how a polypeptide is initially selected for ERAD remains poorly defined. To address this question while co...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Preston, G. Michael, Guerriero, Christopher J., Metzger, Meredith B., Michaelis, Susan, Brodsky, Jeffrey L.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912696/
https://ncbi.nlm.nih.gov/pubmed/29677492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.03.016
Oznake: Označite
Brez oznak, prvi označite!