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Degradation of integral membrane proteins modified with the photosensitive degron module requires the cytosolic endoplasmic reticulum–associated degradation pathway

Protein quality mechanisms are fundamental for proteostasis of eukaryotic cells. Endoplasmic reticulum–associated degradation (ERAD) is a well-studied pathway that ensures quality control of secretory and endoplasmic reticulum (ER)–resident proteins. Different branches of ERAD are involved in degrad...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Scheffer, Johannes, Hasenjäger, Sophia, Taxis, Christof
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740197/
https://ncbi.nlm.nih.gov/pubmed/31411939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-12-0754
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