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Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein

The presence of two basic amino acids strategically located within a single spanning transmembrane region has previously been shown to act as a signal for the endoplasmic reticulum associated degradation (ERAD) of several polypeptides. In contrast, the functionality of this degron motif within the c...

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Autors principals: Ray-Sinha, Arpita, Cross, Benedict C.S., Mironov, Aleksandr, Wiertz, Emmanuel, High, Stephen
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428838/
https://ncbi.nlm.nih.gov/pubmed/19878048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09687680903333839
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