Dislocation and degradation of proteins from the endoplasmic reticulum

Por Wiertz, Emmanuel., Kikkert, Marjolein.
Publicado em 2005

Herpesvirus Interference with Major Histocompatibility Complex Class II-Restricted T-Cell Activation

Por Wiertz, Emmanuel J., Devlin, Robert, Collins, Helen L., Ressing, Maaike E.
Publicado em 2007

Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein

Por Ray-Sinha, Arpita, Cross, Benedict C.S., Mironov, Aleksandr, Wiertz, Emmanuel, High, Stephen
Publicado em 2009

Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

Por Ye, Yihong, Shibata, Yoko, Kikkert, Marjolein, van Voorden, Sjaak, Wiertz, Emmanuel, Rapoport, Tom A.
Publicado em 2005

The HCMV Gene Products US11 and US2 Differ in Their Ability to Attack Allelic Forms of Murine Major Histocompatibility Complex (MHC) Class I Heavy Chains

Por Machold, Robert P., Wiertz, Emmanuel J.H.J., Jones, Thomas R., Ploegh, H.L.
Publicado em 1997

CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases

Por Pabarcus, Michael K., Hoe, Nicholas, Sadeghi, Sheila, Patterson, Cam, Wiertz, Emmanuel, Correia, Maria Almira
Publicado em 2008

Comprehensive profiling of functional Epstein-Barr virus miRNA expression in human cell lines

Por Hooykaas, Marjolein J. G., Kruse, Elisabeth, Wiertz, Emmanuel J. H. J., Lebbink, Robert Jan
Publicado no BMC Genomics (2016)

Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol

Por Luteijn, Rutger David, Drexler, Ingo, Smith, Geoffrey L., Lebbink, Robert Jan, Wiertz, Emmanuel J. H. J.
Publicado no J Gen Virol (2018)

Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3

Por Wang, Xiaoli, Herr, Roger A., Chua, Wei-Jen, Lybarger, Lonnie, Wiertz, Emmanuel J.H.J., Hansen, Ted H.
Publicado em 2007

The E3 Ubiquitin Ligases Hrd1 and gp78 Bind to and Promote Cholera Toxin Retro-Translocation

Por Bernardi, Kaleena M., Williams, Jeffrey M., Kikkert, Marjolein, van Voorden, Sjaak, Wiertz, Emmanuel J., Ye, Yihong, Tsai, Billy
Publicado em 2010

Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates

Por Wang, Xiaoli, Herr, Roger A., Rabelink, Martijn, Hoeben, Rob C., Wiertz, Emmanuel J.H.J., Hansen, Ted H.
Publicado em 2009

TAP Mediates Import of Mycobacterium tuberculosis-Derived Peptides into Phagosomes and Facilitates Loading onto HLA-I

Por Harriff, Melanie J., Burgdorf, Sven, Kurts, Christian, Wiertz, Emmanuel J. H. J., Lewinsohn, Deborah A., Lewinsohn, David M.
Publicado em 2013

Dislocation of Type I Membrane Proteins from the ER to the Cytosol Is Sensitive to Changes in Redox Potential

Por Tortorella, Domenico, Story, Craig M., Huppa, Johannes B., Wiertz, Emmanuel J.H.J., Jones, Thomas R., Ploegh, Hidde L.
Publicado em 1998

Two mechanistically distinct immune evasion proteins of cowpox virus combine to avoid antiviral CD8 T cells

Por Byun, Minji, Verweij, Marieke C., Pickup, David J., Wiertz, Emmanuel J. H. J., Hansen, Ted H., Yokoyama, Wayne M.
Publicado em 2009

MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation

Por Burr, Marian L., van den Boomen, Dick J. H., Bye, Helen, Antrobus, Robin, Wiertz, Emmanuel J., Lehner, Paul J.
Publicado em 2013

The DNase of Gammaherpesviruses Impairs Recognition by Virus-Specific CD8(+) T Cells through an Additional Host Shutoff Function

Por Zuo, Jianmin, Thomas, Wendy, van Leeuwen, Daphne, Middeldorp, Jaap M., Wiertz, Emmanuel J. H. J., Ressing, Maaike E., Rowe, Martin
Publicado em 2008

RNA accessibility impacts potency of Tough Decoy microRNA inhibitors

Por Hooykaas, Marjolein J. G., Soppe, Jasper A., De Buhr, Hendrik M., Kruse, Elisabeth, Wiertz, Emmanuel J. H. J., Lebbink, Robert J.
Publicado no RNA Biol (2018)

Bovine Herpesvirus 1 UL49.5 Protein Inhibits the Transporter Associated with Antigen Processing despite Complex Formation with Glycoprotein M

Por Lipińska, Andrea D., Koppers-Lalic, Danijela, Rychłowski, Michał, Admiraal, Pieter, Rijsewijk, Frans A. M., Bieńkowska-Szewczyk, Krystyna, Wiertz, Emmanuel J. H. J.
Publicado em 2006

Epstein-Barr virus BILF1 evolved to downregulate cell surface display of a wide range of HLA class I molecules through their cytoplasmic tail

Por Griffin, Bryan D., Gram, Anna M., Mulder, Arend, Van Leeuwen, Daphne, Claas, Frans H. J., Wang, Fred, Ressing, Maaike E., Wiertz, Emmanuel
Publicado em 2013

Viral Inhibition of the Transporter Associated with Antigen Processing (TAP): A Striking Example of Functional Convergent Evolution

Por Verweij, Marieke C., Horst, Daniëlle, Griffin, Bryan D., Luteijn, Rutger D., Davison, Andrew J., Ressing, Maaike E., Wiertz, Emmanuel J. H. J.
Publicado no PLoS Pathog (2015)