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Bovine Herpesvirus 1 UL49.5 Protein Inhibits the Transporter Associated with Antigen Processing despite Complex Formation with Glycoprotein M

Bovine herpesvirus 1 (BHV-1) interferes with peptide translocation by the transporter associated with antigen processing (TAP). Recently, the UL49.5 gene product of BHV-1 was identified as the protein responsible for the observed inhibition of TAP. In BHV-1-infected cells and virions, the UL49.5 pro...

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Autori principali: Lipińska, Andrea D., Koppers-Lalic, Danijela, Rychłowski, Michał, Admiraal, Pieter, Rijsewijk, Frans A. M., Bieńkowska-Szewczyk, Krystyna, Wiertz, Emmanuel J. H. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472560/
https://ncbi.nlm.nih.gov/pubmed/16731921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02707-05
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