Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

Detection and elimination of virus-infected cells by cytotoxic T lymphocytes depends on recognition of virus-derived peptides presented by MHC class I molecules. A critical step in this process is the translocation of peptides from the cytoplasm into the endoplasmic reticulum by the transporter asso...

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Detalles Bibliográficos
Autores principales: Koppers-Lalic, Danijela, Reits, Eric A. J., Ressing, Maaike E., Lipinska, Andrea D., Abele, Rupert, Koch, Joachim, Rezende, Marisa Marcondes, Admiraal, Pieter, van Leeuwen, Daphne, Bienkowska-Szewczyk, Krystyna, Mettenleiter, Thomas C., Rijsewijk, Frans A. M., Tampé, Robert, Neefjes, Jacques, Wiertz, Emmanuel J. H. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC555605/
https://ncbi.nlm.nih.gov/pubmed/15793001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501463102
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