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Adhesion inhibition “in vitro” by heparin derivatives correlates with their activity on angiogenesis in mice

Heparin (HEP) play an important role in angiogenesis. Inhibition of matrix degrading enzymes and binding to adhesion molecules are some of the interaction mechanism. The bleeding risk and the need of parenteral administration, restrict the therapeutic use of HEP as angiogenesis modulator, presently...

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Pubblicato in:J Cell Mol Med
Autori principali: Savu, Simona Rizea, Silvestro, L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740101/
https://ncbi.nlm.nih.gov/pubmed/12927058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2003.tb00218.x
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