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Unfractionated Heparin Promotes Osteoclast Formation in Vitro by Inhibiting Osteoprotegerin Activity

Heparin has been proven to enhance bone resorption and induce bone loss. Since osteoclasts play a pivotal role in bone resorption, the effect of heparin on osteoclastogenesis needs to be clarified. Since osteocytes are the key modulator during osteoclastogenesis, we evaluated heparin’s effect on ost...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Li, Binghan, Lu, Dan, Chen, Yuqing, Zhao, Minghui, Zuo, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849062/
https://ncbi.nlm.nih.gov/pubmed/27110777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040613
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