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In vitro and in vivo correlation of clotting protease activity: Effect of heparin

The thrombogenicity of three highly purified proteases (thrombin, activated Factor X, and activated Factor IX) was determined quantitatively in an animal model. The minimal amounts required to produce a standard score 4 thrombus were 1.1 nmol for thrombin, 0.12 nmol for activated Factor X, and 0.018...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Gitel, Sanford N., Stephenson, Ronald C., Wessler, Stanford
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1977
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431395/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/268650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.7.3028
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