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In vitro and in vivo correlation of clotting protease activity: Effect of heparin
The thrombogenicity of three highly purified proteases (thrombin, activated Factor X, and activated Factor IX) was determined quantitatively in an animal model. The minimal amounts required to produce a standard score 4 thrombus were 1.1 nmol for thrombin, 0.12 nmol for activated Factor X, and 0.018...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1977
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431395/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/268650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.7.3028 |
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