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Tissue concentration of heparin, not administered dose, correlates with the biological response of injured arteries in vivo

Drug activity is often studied in well controlled and characterized cellular environments in vitro. However, the biology of cells in culture is only a part of the tissue behavior in vivo. Quantitative studies of the dose response to drugs in vivo have been limited by the inability to reliably determ...

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Detalhes bibliográficos
Main Authors: Lovich, Mark A., Edelman, Elazer R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17995/
https://ncbi.nlm.nih.gov/pubmed/10500138
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