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Adhesion inhibition “in vitro” by heparin derivatives correlates with their activity on angiogenesis in mice

Heparin (HEP) play an important role in angiogenesis. Inhibition of matrix degrading enzymes and binding to adhesion molecules are some of the interaction mechanism. The bleeding risk and the need of parenteral administration, restrict the therapeutic use of HEP as angiogenesis modulator, presently...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Autores principales: Savu, Simona Rizea, Silvestro, L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740101/
https://ncbi.nlm.nih.gov/pubmed/12927058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2003.tb00218.x
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