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Adhesion inhibition “in vitro” by heparin derivatives correlates with their activity on angiogenesis in mice

Heparin (HEP) play an important role in angiogenesis. Inhibition of matrix degrading enzymes and binding to adhesion molecules are some of the interaction mechanism. The bleeding risk and the need of parenteral administration, restrict the therapeutic use of HEP as angiogenesis modulator, presently...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Savu, Simona Rizea, Silvestro, L.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740101/
https://ncbi.nlm.nih.gov/pubmed/12927058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2003.tb00218.x
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