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SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells

Background: Mortalin/GRP-75/mt-hsp70 is a mitochondrial chaperone protein, found in the cytoplasm, endoplasmic reticulum and cytoplasmic vesicles. It functions in many cellular processes such as mitochondrial biogenesis, intracellular trafficking, cell proliferation, signaling, immortalization and t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Huang, Ming-Bo, Wu, Jennifer Y., Lillard, James, Bond, Vincent C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739210/
https://ncbi.nlm.nih.gov/pubmed/31534628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27138
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