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Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells

PURPOSE: Discovery and development of a novel anticancer PEG-SMR-Clu peptide to prevent breast cancer metastasis. How breast cancer cells and primary mammary epithelial cells interact and communicate with each other to promote tumorigenesis and how to prevent tumor metastasis has long been a concern...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Huang, Ming-Bo, Gonzalez, Ruben R., Lillard, James, Bond, Vincent C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355266/
https://ncbi.nlm.nih.gov/pubmed/28076321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14513
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