Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells

PURPOSE: Discovery and development of a novel anticancer PEG-SMR-Clu peptide to prevent breast cancer metastasis. How breast cancer cells and primary mammary epithelial cells interact and communicate with each other to promote tumorigenesis and how to prevent tumor metastasis has long been a concern...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Huang, Ming-Bo, Gonzalez, Ruben R., Lillard, James, Bond, Vincent C.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355266/
https://ncbi.nlm.nih.gov/pubmed/28076321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14513
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